The best month to fly between Amsterdam and Rome is January and the most expensive month to fly is December. (Average prices, based on 337 datapoints.)
The best day to arrive at Amsterdam is Tuesday and it would be best to avoid Saturday, as prices are on average 57.54% higher than on Tuesday. (Average prices, based on 1288 datapoints.)
The best time to fly is at around 11. (Average prices, based on 604 datapoints.)