Flight Benazir Bhutto International Airport departs from Islamabad Benazir Bhutto International Airport at 05:30 and arrives at Istanbul Sabiha Gökcen International Airport at 09:45.
The flighttime is about 6h 15m. The distance travelled ("as the bird flies"): 4888 Km. So the average speed is roughly 782 Km.
There is an 2 hour time difference between Islamabad and Istanbul